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From: Michelle D.
Date: 1/31/2002
Time: 7:15:45 AM
Remote Name: 205.188.193.42
Anne, I just spent a half an hour writing you a post and filled with a bunch of typed info and lost it. I don't know if it is the site or my computer. So, this is my last ditch effort and I hope I can find what it was I wrote the first time. Frustrating these computers sometimes.
Okay. I began with did you get your free testosterone tested? Your SHBG says 151.o nmol/L and you say normal is 20.0 to 120.0. Would that mean you SHBG is high? I am not sure I am reading that correctly. Do you think free androgen index is the same as free testosterone? I am not familiar with that test.
Anyway, I believe it is good to have more SHBG in that it kind of soaks up the androgens and your androgen index was low. So that is good. My tests were always with in range no matter how many times they were run.
I certainly believe that someone can have normal hormones and still have a sensitivity. I would think the same would stand for low too according to what I quoted below (Just my opinion though)
On page 202 in The Good News About Women's Hormones, Dr. Redmond writes:
"Some women with androgen problems have normal testosterone levels. There are several reasons for this. First, the levels fluctuate; by chance, blood may have been taken when the levels happen to be at their lowest. Second, there is a strong tendency for androgen levels to go down with age. Testosterone and all the other androgens are at their highest in the late teens or very early twenties, and they work their way down after that. However, once the hair follicles have been stimulated by higher levels of testosterone, they tend to stay active. High androgens program the hair follicle to be more active indefinitely. "
Pages 192-193 "There are several androgens. Testosterone is the most powerful. Most of it is carried in the blood, attached to a special protein called sex-hormone binding globulin (SHBG). Testosterone attached to this protein cannot move out of the blood into the tissues; SHBG serves as a reservoir of the hormone. Free testosterone is the dissolved form that is not attached to SHBG; it goes out of the blood into the tissues, including target organs, such as the pilosebaccous unit.
Free testosterone can be measured, but the measurement is more difficult than that for total testosterone; only a limited number of labs can perform it accurately. (It is also more expensive.)
My research has convinced me that free testosterone has a much closer relationship to androgenic problems in women than does the cruder measure of total testosterone. If you are being evaluated for an androgenic problem, I recommend that you request this test instead of only the total testosterone measurement. It is worth the extra cost.
Some of the effects of testosterone are due to the hormone itself, but others, especially hair loss, are more related to another form called DHT. DHT is made from testosterone in target tissues, including the pilosebaceous unit, by an enzyme called 5 alpha reductase. It is DHT levels in the skin that are important, so it is not useful to measure it in blood."
You mentioned your FSH levels increasing and your estrogen decreasing.
Page 236-237 " The pill suppresses the secretion of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) by the pituitary gland. The result is suppression of ovulation and partial suppression of hormone secretion by the ovary. Any decrease in estrogen and progesterone is not noticed because these hormones are in the pill. But androgens decrease also, and so the pill can be useful for women with androgenic disorders."
Anne, I just put that in because I came across it and it just sounded interesting. I have a friend who is 50 and is on the BCP. I don't recommend it for everyone. Some people, as already said, have problems with hair loss due to it. I don't and many don't when using a less androgenic form. It is just a way of leveling out the hormones I think. Anyway, I just thought that was interesting.
Anne, I just quoted this stuff to you just as a reference. Again, your situation is complicated and this stuff may or may not apply to you.
My Rosacea technically started around the time of the hair loss. I had a strange sandpaper type rash that I was running around trying to get answers to and trying different concoctions for, but no one ever knew what it was I was really talking about. That went away in two years. But during this time one hair loss doctor said it was Rosacea and prescribed Rogaine and MetroCreme for me. I used the tube and another derm told me he was crazy and I didn't have it.
Five years later I have a tremendous flairup due to C0Q10 and since then it has really been getting worse. I am on antibiotics at the moment and using Noritate twice a day. I think a lot of my flushing is due to hormonal changes at the moment.
Sorry this was so long. Hope you didn't mind and I hope this answered your questions.
My best to you, Michelle D.
From: Abagail
Date: 24 Dec 2007
Time: 01:34:14
Remote Name: 70.87.66.210
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