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Topic 563 - Propecia, Proscar, Finasteride, Arimidex, Loniten, Oral Minoxidil, Spironolaconte et al - forum 17

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Re: cause of propecia side effects

From: Ephemeral Blackjack
Date: 5/9/2002
Time: 11:38:13 PM
Remote Name: 67.240.24.233

Comments

It is from both these effects. The reduction in DHT results in sexual performance difficulties for some men. The increase in estrogen can result in gynecomastia. The basic idea is

Testosterone is converted to DHT by 5AR Type I and Type II enzymes.

AND

Testosterone is converted to estrogen by aromatase enzyme.

When production of DHT from testosterone is blocked by propecia, serum DHT levels decrease and serum testosterone levels increase (because the testosterone is no longer being converted to DHT). The increase in testosterone provides more raw material for the body to produce higher levels of estrogen via the aromatase enzyme. The result, it is harder to lose weight around the abdomin and potentially gynecomastia.

Ephemeral Blackjack

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Date: 15 Dec 2007
Time: 09:51:15
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