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From: TriedItAll
Date: 10/24/2002
Time: 6:31:32 PM
Remote Name: 63.57.247.204
There is no "Hypothalamic-Pituitary-testicular" axis. The HPT axis is the Hypothalamic-Pituitary Thyroid axis. What you are referring to is the Hypothalamic-Pituitary-Gonad Axis (HPG). Sorry, I don't know who started using that phrase (and yes, I've seen it too) but it is incorrect and a pet peeve of mine. Anyway, negative feedback in the HPG axis, much like the HPA and HPT axis, functions in most cases with timing similar to circadian rhythms. In other words, what you are talking about are the daily hormone level fluctuations (short loop negative feedback). I am talking about TOTAL suppression of both DHT and Estrogen. Yes, this would result in a SHORT-TERM increase in testosterone, but would eventually cause the gonads to stop producing Luteinizing (and yes, I've seen it spelled Leutinizing) hormone. This would result in lowered levels of tesosterone for a long period of time. Eventually, Test levels would rise again and go through the same process, but not in one day. The point is that this long term fluctuation would cause problems on a grand scale, mostly when LH and FSH production are low. Just because estrogen and DHT levels would be nearly non-existent doesn't mean the body would produce more testosterone indefinitely. What you are referring to is the body trying to remain in balance. I am referring to a state where balance isn't possible.
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